Thorne’s 5-MTHF provides 1 mg of the active form of folate (as Quatrefolic®) per capsule.
This ready-to-use folate is essential for methylation, supporting neurological, cardiovascular, and prenatal health without the need for conversion by the body.
Select probiotics only. Online shop only. Valid only through 3/31/26.
Online shop only. Valid only through 3/23/26.
$24.00 — or subscribe to save 5%
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Unlock the full benefits of folate with Thorne’s 5-MTHF (5-Methyltetrahydrofolate).
Unlike synthetic folic acid, which requires a multi-step enzymatic conversion to become active, 5-MTHF is the predominant, ready-to-use form of folate found in the bloodstream. This makes it the superior choice for individuals, including those with common genetic variations (such as MTHFR), who may have difficulty efficiently converting folic acid.
This supplement features Quatrefolic®, a premium, well-researched form of 5-MTHF that is highly stable and bioavailable. Each capsule delivers a potent 1 mg dose to support critical bodily functions, including DNA synthesis, neurotransmitter production, and cardiovascular health.
By providing folate in its active form, Thorne ensures your cells can immediately utilize this vital nutrient for optimal health from the moment you take it.
Take 1 capsule one to three times daily or as recommended by your healthcare practitioner.
Since individual needs vary, especially regarding MTHFR status, it is best to consult with a healthcare provider to determine the optimal dosage for you.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent disease.
Complement your routine and enhance your results. These related supplements work together for a more comprehensive approach to your wellness goals.
Fuel your metabolism and support your healthy weight goals. These supplements are designed to help manage appetite and enhance your body’s natural fat-burning processes.
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All ClearSpring Pharmacy locations will be closed in observance of Memorial Day, Saturday, July 4th, 2026.
Normal business hours will resume on Monday.
A nationwide shortage of estradiol patches is affecting major pharmacies and may continue for up to 3 years.
Affected brands include:
You don’t need to wait until you run out. Compounding pharmacies are experts at stepping in when drug shortages occur.
We have topical options such as creams or troches, and we work with your doctor to ensure your care stays on track.