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SPM Active One Daily - 60 Softgels
SPM Active One Daily - 1 Softgel
SPM Active One Daily - Supplement Facts

SPM Active One Daily – 60 Softgels

SPM Active® One Daily helps your body feel better—fast. In just 14 days, this once-a-day softgel helps ease everyday soreness and joint discomfort so you can move more freely.*†

60 Softgels

10% Off

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Use Code: PROBIOTICS2026

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Entire Store
Use Code: STARTSPRING26

Online shop only. Valid only through 3/23/26.

$124.95 — or subscribe to save 5%

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About SPM Active One Daily – 60 Softgels

Clinically Studied, Next-Generation Fish Oil: Delivers specialized pro-resolving mediators (SPMs)—compounds derived from concentrated omega-3s that help ease minor joint discomfort and support faster recovery after physical stress or exercise.*

Renews the Body’s Natural Ability to Relieve Discomfort: Scientifically formulated to support the body’s natural inflammatory process—rather than simply mask symptoms—to help promote long-term joint and tissue health.*

Convenient Once-Daily Dose: Requires only one easy-to-swallow softgel per day to help maintain comfort with a simple daily routine.

Benefits Overview

  • Relieves everyday soreness to help you feel more comfortable.*
  • Supports joint health so you can stay active with ease.*
  • Helps your body bounce back after physical activity or daily stress.*
  • Promotes relief by complementing the SPMs naturally produced in your body.*
  • Case studies show taking SPM Active® daily for 8 weeks led to improvements in mood, mental clarity, stress, and fatigue.*
  • Within 24 hours, immune cells respond smarter—strengthening protection while reducing damage to your body.*††
  • Specialized pro-resolving mediators (SPMs) are concentrated lipid compounds derived from omega-3 fatty acids in fish oil that support the body’s natural ability to resolve soreness and inflammation.*
  • SPMs are naturally found in the body, but our SPM levels decrease as we age, leading to increased rates of muscle and joint soreness.*
  • Metagenics pioneered supplementation of SPMs, offering the first-ever SPM product to help you reduce joint pain and soreness, and boost immune response.*

Supplement Use

  • Dosage: Take one softgel once daily or as directed by your healthcare practitioner.
  • Best For: Adults seeking effective relief for body soreness and joint discomfort. If you are pregnant, nursing, or taking medication, consult your healthcare practitioner before use. Keep out of the reach of children.
  • Safe for Daily Use: Safe and gentle for everyday use—one softgel per day.

Supplement Facts Overview

  • Clinically Studied, Next-Generation Fish Oil: Delivers specialized pro-resolving mediators (SPMs)—compounds derived from concentrated omega-3s that help ease minor joint discomfort and support faster recovery after physical stress or exercise.*
  • Renews the Body’s Natural Ability to Relieve Discomfort: Scientifically formulated to support the body’s natural inflammatory process—rather than simply mask symptoms—to help promote long-term joint and tissue health.*
  • Convenient Once-Daily Dose: Requires only one easy-to-swallow softgel per day to help maintain comfort with a simple daily routine.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent disease.

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Ask Us A Question!

Our on-staff nutrition experts are quick to respond and can answer any questions, curiosities, or concerns you may have about our products.

Call Us or Text Us: (719) 455-8035

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Closed For Memorial Day

All ClearSpring Pharmacy locations will be closed in observance of Memorial Day, Monday, May 25th, 2026. 

Normal business hours will resume the following day.

With the Busy Holiday Season

Please Allow Extra Time For Prescriptions

The holidays bring us joy, but they also bring us more prescriptions to fill and ship. Our pharmacy continues to work diligently, but an increase in demand may result in slightly longer processing times.

Please consider doing the following:

  • Anticipate and account for the mail system taking a bit longer.
  • Request refills earlier.
  • Keep track of the amount of medication you have left.

Thank you,
ClearSpring Team