Side Effects of Trimix Injections and How to Manage Them

Managing Trimix Injection Reactions

When patients who have erectile dysfunction (ED) fail to find relief from oral medications, physicians will commonly prescribe trimix injections.

As with any prescription medication, it is important to understand the potential side effects and how to manage them. Possible reactions range from common to rare, where providers should be notified.

So which side effects should you look out for?

Frequently Asked Questions

How Fast Does Trimix Take Effect?

Patients using trimix will typically gain an erection 5 to 15 minutes after the injection.

How Long Can I Store Trimix?

When stored in the freezer, trimix can last around 45 days before needing to be used.

Trimix should be thawed out at room temperature for a few minutes before use.

How Much Trimix Should I Use?

Typical starting doses of trimix range from 5 to 20 units based on prescriber recommendations.

From there, increases can be made 5 units at a time with a maximum of 50 units possible.

Does Trimix Cure ED?

Trimix does not cure ED.

It only provides a means to an erection firm enough for sex after injection. ED symptoms may persist when not used.

Can I Take Viagra and Trimix Together?

It is generally not recommended to take trimix in conjunction with other erectile dysfunction treatments like Viagra unless recommended by a doctor.

Taking both can lead to priapism (prolonged erection) or a severe drop in blood pressure.

Potential Trimix Side Effects

Common Reactions

Some patients may experience these minor side effects, especially with consistent use. They are often temporary and localized.

Minor Bleeding or Bruising: Usually occurs at the injection site.
Mild Aching or Pain: Some men report a dull ache during or after an erection.
Fibrosis: Repeated injections may lead to hardened scar tissue. We recommend rotating injection sites to manage the risk.

Less Common, More Serious Reactions

You should seek medical attention if you experience these side effects.

Priapism: A prolonged erection lasting more than four hours. This condition can lead to permanent tissue damage if not addressed by a healthcare professional. It is considered a urological emergency.
Dizziness or Lightheadedness: May be due to hypotension (very low blood pressure), which can lead to fainting or other serious complications.

Guidance on Use and Management

Injection Technique

Proper administration can help reduce certain reactions.

Use the trimix needle size specified by your pharmacist.
Inject into the side of the penis at a 90-degree angle, avoiding visible veins.
Apply pressure after injection.

Dosage and Frequency

Make sure to adhere to the prescribed dosage. Your healthcare providers work with you to optimize the dose on an individual basis.

Your doctor will determine a starting dose, which they may adjust based on your response.
Do not change your dose without consulting your prescriber.

Considerations for Long-Term Use

Using trimix long-term can lead to fibrosis or a change in response to the medication. Your doctor will monitor your use to keep track of these potential side effects and make adjustments accordingly.

Is Trimix Worth Considering?

Just like any medication, patients are encouraged to consider the benefits as well as the potential side effects. Many patients find success with trimix after not seeing results from oral tadalafil or sildenafil.