Bioidentical hormones are lab-created molecules that precisely match the hormones your body produces (like estrogen, progesterone, testosterone, and cortisol).
They are derived from plant sources, such as wild yam or soy, and modified to be structurally identical to human hormones.
Many patients prefer bioidentical hormones for this reason. They will opt for hormones that are organic and molecularly similar to the hormones our body produces, rather than synthetic and molecularly different.
They're derived from plants but processed in a lab. "Bioidentical" refers to their molecular structure, not their source.
Absolutely!
We help providers transition patients safely.
Signs that you may need HRT include:
It is necessary to consult with your doctor to determine if the symptoms you are experiencing are caused by a hormonal imbalance rather than another condition.
Yes.
Blood tests every 6–12 months check hormone levels, liver function, and cardiovascular markers.
We provide dosing support based on your results.
Most women notice initial improvements, such as fewer hot flashes and improved sleep, within 2-4 weeks of starting HRT.
Full benefits, such as a balanced mood, sustained energy, and improved vaginal health, typically develop within 2-3 months.
Long-term protective effects, such as osteoporosis prevention, are typically noticed after 1 year or more of consistent use.
Always collaborate with your provider to fine-tune your treatment.
| Bioidentical Hormones | Synthetic Hormones | |
|---|---|---|
| Molecular Structure | Identical to human hormones | Different from human hormones |
| Source | Plant based (wild yam, etc.) | Animal/Petrochemical derived |
| Customization | Tailored doses and forms | Fixed doses and forms |
| Common Forms | Creams, troches, capsules | Pills, patches, injections |
Your body has hormone receptors that interact with the hormones it produces. There are specific hormone receptors that correspond to each hormone.
If we think of each receptor as a “lock,” then the hormone would function as a “key.” Using the proper key to unlock the receptor will elicit a reaction in the cell. In many cases, it helps restore cellular function and maintain balance in the system.
Since bioidentical hormones mimic the “keys” our body naturally produces, they can create the desired reaction and metabolize naturally.
Synthetic hormones function more like “broken keys.“
Rather than naturally bind to our hormone receptors, they force interactions. Our body then needs to do more work to break it down into a usable form.
The metabolization of synthetic hormones is slower and differs from bioidentical hormones. This exchange can lead to side effects such as bloating, blood clots, mood swings, or increased risk of stroke.
Not all hormones work the same way for every person. That’s why bioidentical hormone therapy (BHRT) offers multiple delivery methods.
Each form can offer its own unique benefits and uses.
Bioidentical hormone creams and gels work by being absorbed directly through the skin into the bloodstream, delivering steady and sustained hormone levels.
This transdermal method bypasses the digestive system entirely, increasing its ability to be absorbed and take effect (bioavailability).
These formulations dissolve under the tongue or in the cheek. Hormones are delivered directly into the bloodstream, avoiding first-pass metabolism in the liver.
Patients often use this delivery method for time-sensitive needs such as perimenopause fluctuations, acute anxiety episodes, and thyroid hormone support.
This medication form delivers hormones directly to vaginal and urethral tissues. Patients will use this form for targeted relief of genitourinary symptoms like dryness, pain, and recurrent UTIs.
Though less is absorbed into the bloodstream, the targeted approach helps address localized symptoms.
Time-released capsules dissolve gradually in the digestive tract, providing systemic hormone support that is ideal for addressing adrenal or thyroid imbalances.
Capsules are great for customization and combining different hormones into a single medication.
One size doesn’t fit all. And this is especially true for BHRT.
| How It Works | Best For | |
|---|---|---|
| Creams/Gels | Absorbed through skin | Steady dosing (e.g., estrogen) |
| Sublingual Drops & Troches | Melt under tongue | Fast relief (hot flashes) |
| Vaginal Inserts & Creams | Targeted delivery | Vaginal dryness/UTIs |
| Capsules | Time-released in gut | Adrenal/thyroid support |
While bioidentical hormones are often better tolerated than synthetics, they carry similar risks, including blood clots and stroke. These risks are higher for smokers and patients with clotting disorders.
Hormone replacement therapy has also been linked to cases of cancer. When taking estrogen or progesterone, patients see an increased risk of breast or endometrial cancer.
It is important to talk to a doctor about the associated risks of hormone replacement therapy.
Precise dosing, ingredient control, and vigilant monitoring help manage unwanted side effects from HRT.
Compounding pharmacies provide targeted doses, even those not available commercially. This dosing method minimizes overexposure and ensures the prescription meets the patient’s specific needs.
Having complete control over the ingredients also allows us to exclude additives that trigger allergies. Patients who are sensitive or irritated by ingredients in a commercial medication can have it removed through a compounding pharmacy.
Consistent monitoring is crucial for patients taking BHRT. Regular provider check-ins and blood tests every 3-6 months are recommended to adjust your therapy and detect issues early.
Your pharmacy should work closely with your doctor to review your lab results and symptoms, ensuring your treatment evolves in line with your body’s changing needs.
Bioidentical hormone therapy isn’t a one-size-fits-all solution, it’s a personalized partnership between you, your provider, and your compounding pharmacy.
We’ve helped thousands in Littleton, Cherry Creek, and beyond restore energy, sleep, and vitality through precision-dosed therapies that align with your unique biology.
For questions, fill out our form. Or have your provider contact us to fill your prescription!
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