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Intolerance Complex

Provides specialized enzymes for the most common food intolerances.*


  • High-potency digestive enzyme blend
  • Specialized for gluten, casein, lactose, complex carbohydrate and phenol sensitivities*
  • Contains additional enzymes for fat, fiber, protein, and carbohydrate digestion *



More Information

Intolerance Complex offers a broad approach to digestive sensitivities.* This unique formula was crafted to cover all of the major food intolerances in a single capsule.*

Unlike food allergies, which are an immune reaction, food intolerance is a digestive occurrence caused by an insufficient quantity of a particular enzyme to digest the offending food.  Intolerance can manifest as occasional diarrhea, bloating, cramping or upset stomach.  By supplementing the digestive system with targeted enzymes, the body can more efficiently break down foods to lessen or prevent symptoms that are common to food intolerance.*  Intolerance Complex gives your body what it needs to enjoy the foods you love.

Enzyme Science formulates each enzyme focused product with exclusive Thera-blend enzymes. The Thera-blend process is scientifically designed to provide optimal solutions for digestive health and wellness.  These unique protease, amylase, cellulase and lipase enzymes are comprised of multiple variants which are blended to work synergistically throughout the broad pH range of the human body.

Food intolerance occurs when the body has difficulty digesting certain foods. This sensitivity manifests itself as occasional indigestion, bloating, diarrhea, gas, and overall abdominal discomfort. Since there may be overlap of gastrointestinal symptoms between food allergy and intolerance, individuals often confuse the two. In contrast to a food allergy, food intolerance does not involve the immune system nor presents life-threatening reactions. While allergies are brought on by an adverse reaction to specific food proteins, symptoms of intolerance are brought on by a lack of enzymes to properly break down food.

The most common foods individuals have difficulty digesting include lactose (dairy sugar), casein (dairy protein), gluten (protein from grains—wheat, barley, oats, and rye), phenols (naturally occurring compounds in plants), and complex carbohydrates (vegetables, legumes, grains, cereals, nuts, and seeds).

Considering enzymes cleave very specific bonds on a single substrate, it is essential to have sufficient enzymes for not only general protein, carbohydrate, fat, and fiber digestion, but also enzymes specialized for digesting food components common to food intolerance. Intolerance Complex™ includes a multitude of high potency protease, amylase, lipase, and cellulase including enzymes dipeptidyl peptidase IV (DPP-IV), lactase, xylanase, and alpha-galactosidase for targeted gluten, dairy, phenol, and complex carbohydrate digestion.*

A human clinical study published in Clinical and Translational Gastroenterology has shown that administering a mixture of digestive enzymes significantly improved the symptoms of non-celiac gluten sensitivity.* The proteolytic enzyme dipeptidyl peptidase IV (DPP-IV) has demonstrated the ability of breaking down moderate amounts of both gluten (wheat protein) and casein (dairy protein) which are common to intolerance.* Lactase enzyme supplementation has been shown to efficiently digest lactose and alleviate abdominal discomfort.* With natural levels of lactase diminishing significantly with age, lactase supplementation is essential for optimal digestion.*

Those who have physical symptoms after consuming foods rich in phenolic compounds such as berries, citrus fruits, vegetables, grains, spices, coffee, or red wine, may be intolerant to phenols. Even though these foods provide great antioxidant benefits, some individuals find these compounds difficult to digest and metabolize. Xylanase breaks down components of plant cell walls to aid in proper digestion which allows for valuable nutrients to be available to the body.* Undigested complex carbohydrates also cause digestive discomforts like gas and bloating. Studies have shown that supplementing with carbohydrate-and starch-digesting enzymes including alpha-galactosidase, hemicellulase, and cellulase result in a reduction in gas production and related abdominal symptoms.*

Enzyme Science® formulates with unique protease, amylase, cellulase, and lipase enzymes that are scientifically designed to provide optimal solutions for digestive health and wellness.* While individual enzymes work within a specific pH or pH range, Thera-blend enzymes remain active across a broad pH range allowing greater interactions with substrates to promote superior digestion.* In addition to Thera-blend enzymes, Intolerance Complex™ includes enzymes such as glucoamylase, pectinase, maltase, invertase, and hemicellulase to further promote digestion of the entire meal.*
As an added benefit, Intolerance Complex features the blend, ATPro™, consisting of ATP, magnesium citrate, phytase, and Coenzyme Q10. Metabolic reactions utilize nutrients to produce ATP, adenosine triphosphate, the body’s energy source. ATP is used to power energy-requiring cellular or enzymatic reactions and is vital for muscle contraction during digestion. Phosphate, required for ATP synthesis, is released from phytic acid found in foods by the enzymatic action of phytase. CoQ10 is fundamental in ATP production and ATP must bind to magnesium to be biologically active. Replenishing ATP and supporting ATP production through the actions of CoQ10, magnesium citrate and phytase from ATPro™ further encourages digestive health.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent disease.

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