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Low-Dose Naltrexone Benefits

The Upsides of Low-Dose Naltrexone

Many patients have turned to low-dose naltrexone (LDN) to help with various conditions. LDN has shown the propensity to help with pain, mental health, autoimmune diseases, and more.

LDN helps with these conditions by providing the following benefits:

Increasing Endorphins

When used at traditional doses, naltrexone completely blocks opioid receptors. This reduces the euphoric effects of addictive drugs such as heroin or opioids.

At lower doses, however, naltrexone only temporarily blocks the same opioid receptors. The intermittent blocking causes the body to generate up to 3x more endorphins!

The increase in endorphins is the main driver for several additional benefits.

Reduced Inflammation

Boosting endorphin production will help reduce inflammation due to autoimmune disorders.

Beta-endorphins can have an inhibitory effect on the production of antibodies, leading to a reduced cytokine response. 

LDN also eases inflammation by impairing glial cell cascadingThis provides relief from conditions like fibromyalgia, where chronic glial cell activation increases inflammation.

Decreased Pain

Many patients use LDN to help with chronic pain conditions, including:
  • Fibromyalgia
  • Neuropathic pain
  • Complex regional pain syndrome (CRPS)

Along with anti-inflammatory capabilities, LDN also provides analgesic effects. These effects take time, however. Patients can expect relief to occur anywhere from 2 to 8 weeks.

Minimal Side Effects

One of the most significant benefits of using LDN is that it has minimal to no side effects. Patients are not at risk for addiction and have no withdrawal symptoms if they choose to stop taking the medication.

Some patients will experience:
  • Vivid dreams or sleep disturbances
  • Gastrointestinal upset 
  • Nausea
  • Mild headache
  • Mild agitation

However, only some patients will experience these side effects. Pharmacists can minimize side effects by starting at low doses and slowly working up.

Less Reliant on Medications

Treating conditions such as chronic pain and autoimmune disease can be difficult. Traditional approaches may even incorporate multiple medications, including opioids. LDN helps eliminate the reliance on these additional drugs.

Many patients have satisfactory results when using LDN for their chronic pain or autoimmune conditions. Medications such as opioids can lead to addiction and other adverse outcomes. LDN helps patients step away from these medications.

Improved Quality of Life

All in all, LDN helps give patients their lives back. Many patients have found success with LDN and have been symptom-free from illnesses such as fibromyalgia and Crohn’s disease

Patients report increased quality of life while using LDN and even a few weeks post-LDN use. This is invaluable for patients who have tried other treatments to no avail.

Interested in LDN? Reach Out!

LDN is an off-label product. It needs to be prescribed to a compounding pharmacy. ClearSpring has over 20 years of experience compounding medications and works with LDN patients regularly.

Please get in touch with our pharmacists if you have any questions about LDN. We can help you decide if it’s right for you.

You can also text us directly here:
Littleton: 303-707-1500
Cherry Creek: 303-333-2010

Or send us a message on social media! Follow us and get a peek at how we make our medications in the lab.